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中国科学院生态环境研究中心 马梅 女 博导
 

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研究领域

   

招生信息

   
招生专业
083001-环境科学
招生方向
水生态毒理学

教育背景

1996-09--中科院生态环境研究中心   博士
1986-09--北京大学医学部药学院化学与生物学系   理学学士
学历
   
学位
   

工作经历

   
工作简历
2008-03~现在, 中科院生态环境研究中心, 研究员
2001-12~现在, 中科院生态环境研究中心, 副研究员
1996-09~现在, 中科院生态环境研究中心, 博士
1996-07~现在, 中科院生态环境研究中心, 助理研究员
1991-07~现在, 中科院生态环境研究中心, 研究实习员
1986-09~现在, 北京大学医学部药学院化学与生物学系, 理学学士
社会兼职
   

教授课程

环境水质学

专利与奖励

   
奖励信息
(1) 基于鱼法的生物预警关键技术研究及在北京市南水北调工程中的应用,2016年度北京水务科学技术奖,三等奖,2016。, 三等奖, 其他, 2016
(2) 基于人核受体超家族监测环境内分泌干扰物的新技术及应用, 二等奖, 部委级, 2013
专利成果
( 1 ) 检测类/抗甲状腺激素化合物的双杂交酵母及检测方法, 2011, 第 3 作者, 专利号: 200710308507.3
( 2 ) 检测类/抗维甲酸化合物的双杂交酵母以及生物测试方法, 2011, 第 3 作者, 专利号: 200710308511.X

出版信息

   
发表论文

(1) The Molecular Mechanism of the Antagonistic Activity of Hydroxylated Polybrominated Biphenyl (OH-BB80) toward Thyroid Recepto, Science of the Total Environment, 2019-08, 第 5 作者
(2) Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairments in A549 cells, Environmental Pollution, 2019-07, 第 11 作者
(3) A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro, Ecotoxicology and Environmental Safety, 2019-06, 第 11 作者
(4) Triple functional small-molecule-protein conjugate mediated optical biosensor for quantification of estrogenic activities in water, Environment International, 2019-06, 第 5 作者
(5) Simultaneous passive sampling of hydrophilic and hydrophobic emerging organic contaminants in water, Ecotoxicology and Environmental Safety, 2019-05, 第 11 作者
(6) Insight into the generation of toxic products during chloramination of carbamazepine: Kinetics, transformation pathway and toxicity, Science of the Total Environment, 2019-04, 第 11 作者
(7) Comparative toxicity study of a novel non-ionic surfactant, vanillin ethoxylates, and nonylphenol ethoxylates in Chinese hamster ovary cells in vitro, Journal of environmental sciences, 2019-01, 第 11 作者
(8) 加氯,氯胺和臭氧消毒卡马西平的毒性, Chlorination, chloramination and ozonation of carbamazepine enhance cytotoxicity and genotoxicity: Multi-endpoint evaluation and identification of its genotoxic transformation products, Journal of Hazardous Materials, 2018, 第 11 作者
(9) 氯代多环芳烃的Ah受体效应和DNA损伤效应, The aryl hydrocarbon receptor (AhR) activity and DNA-damaging effects of chlorinated polycyclic aromatic hydrocarbons (Cl-PAHs), Chemosphere, 2018, 第 11 作者
(10) 多种雌激素污染物对MCF-7细胞增殖联合效应的预测及相关基因分析, Prediction of the combined effects of multiple estrogenic chemicals on MCF-7 human breast cancer cells and a preliminary molecular exploration of the estrogenic proliferative effects and related gene expression, Ecotoxicology and Environmental Safety, 2018, 第 11 作者
(11) 十种皮革化学品的细胞和遗传毒性的高内涵分析, In vitro Cytotoxicity and Genotoxicity Analysis of Ten Tannery Chemicals Using SOS/umu Tests and High-content In vitro Micronucleus Tests, Combinatorial Chemistry & High Throughput Screening,, 2018, 第 11 作者
(12) 双酚S的甲状腺受体作用,离体,活体和分子动力模拟研究, Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor β: in Vitro, in Vivo, and Molecular Dynamics Simulation Study, Environ. Sci. Technol, 2018, 第 3 作者
(13) 黄超,李娜,袁圣武,季晓亚,马梅*,饶凯锋,王子健,有机磷阻燃剂诱导的CHO细胞线粒体损伤和死亡机制研究,环境污染,2017,2307,775, Chao Huang, Na Li, Shengwu Yuan, Xiaoya Ji, Mei Ma *, Kaifeng Rao, Zijian Wang,Aryl- and alkyl-phosphorus-containing flame retardants induced mitochondrial impairment and cell death in Chinese hamster ovary (CHO-k1) cells,Environmental Pollution 230 (2017) 775-786, Environmental Pollution, 2017, 第 11 作者
(14) 季晓亚,李娜,袁圣武,黄超,饶凯锋,马梅* ,王子健,环境雌激素生物效应的作用机制研究进展,生态毒理学报,2017,12(1)38-51, Ji Xiaoya , Li Na , Yuan Shengwu , Huang Chao , Rao Kaifeng , Ma Mei* , Wang Zijian,Research Progress in the Mechanisms for Biological Effects of Environmental Estrogens,Asian Journal of Ecotoxicology, 2017 Vol. 12, No.1, 38-51, 生态毒理学报, 2017, 第 11 作者
(15) 环境污染物导致氧化应激的关键信号通路及其检测方法, Yuan Shengwu1,Huang Chao1, Ji Xiaoya1,Ma Mei,Main Signaling Pathways and Detection Methods of Oxidative Stress Caused by Environmental Pollutants,Asian Journal of Ecotoxicology, 2017,12, No.1, 25-37, 生态毒理学报, 2017, 第 11 作者
(16) Development of a data-processing method based on Bayesian k-means clustering to discriminate aneugens and clastogens in a high-content micronucleus assay,, Human and Experimental Toxicology, 2017, 第 11 作者
(17) 59. Na Li, Weiwei Jiang, Mei Ma*, Donghong Wang, Zijian Wang,Chlorination by-products of bisphenol A enhanced retinoid X receptordisrupting effects, Journal of Hazardous Materials, 2016, 第 11 作者
(18) Evaluation of genotoxic effects of surface waters using a battery of Bioassays indicating different mode of action, Ecotoxicology and Environmental Safety, 2016, 第 11 作者
(19) Combined action of estrogen receptor agonists and antagonists in two-hybrid recombinant yeast in vitro, Ecotoxicol. Environ. Saf. 2015, 111(1):228-235, 2015, 第 11 作者
(20) Combined effects of estrogenic chemicals with the same mode of action using an estrogen receptor binding bioassay, Environmental Toxicology and Pharmacology, 2014, 第 11 作者
(21) Application of the SOS/umu test and high-content in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles, Journal of Applied Toxicology, 2014, 第 11 作者
(22) Liu Nannan, Ma Mei, Xu Yiping, Zha Ji nmiao, Rao Kaifeng, Wang Zijian. 2013. Susceptibility of male and female Japanese medaka (Oryzias latipes) to 2,4,6-trichlorophenol-induced micronuclei in peripheral erythrocytes,  Frontiers of Environmental Science &Engineering., 2013, 第 11 作者
(23) Assessment of source water contamination by estrogenic disrupting compounds in China. Journal of Environmental Sciences,  Journal of Environmental Sciences (China),, 2012, 第 11 作者
(24) Retinoid X receptor activities of source waters in China and their removal efficiencies of drinking water treatment processes. , Chinese Science Bulletin, 2012, 第 11 作者
(25) 45. Jianping Luo a,b, Bingli Lei a, Mei Maa, Jinmiao Zha a, Zijian Wang,Identification of estrogen receptor agonists in sediments from Wenyu River, Beijing, China,, water re search, 2011, 第 3 作者
(26) In vitro assay for human thyroid hormone receptor ? agonist and antagonist effects of individual polychlorinated naphthalenes and Halowas mixtures, , Chinese Science Bulletin , 2011, 第 2 作者
(27) Dibutyl Phthalate Contributes to the Thyroid Receptor Antagonistic Activity in Drinking Water Processes, Environmental Science and Technology, 2010, 第 4 作者

 
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